10 Vials of 10mg PT-141 – Lab-tested, high-purity synthetic melanocortin receptor agonist peptide. Supports sexual health, arousal pathway, and CNS motivation research with secure payment and fast, discreet shipping.
PT-141 (Bremelanotide) is a synthetic cyclic heptapeptide and melanocortin receptor agonist, primarily targeting MC3R and MC4R in the central nervous system. Unlike traditional erectile dysfunction treatments, it works centrally in the brain—particularly the hypothalamus—to enhance sexual desire, arousal, and motivation by modulating dopamine, oxytocin, and norepinephrine pathways.
Originally derived from Melanotan II, PT-141 was developed to treat hypoactive sexual desire disorder (HSDD) and erectile dysfunction. It is FDA-approved under the brand name Vyleesi for premenopausal women with HSDD, administered via subcutaneous injection approximately 45 minutes before anticipated sexual activity.
It does not rely on nitric oxide pathways, making it effective for individuals unresponsive to PDE-5 inhibitors like sildenafil. Effects typically begin within 30–60 minutes and last several hours.
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